Madelung's Disease (also called Multiple Symmetrical Lipomatosis [MSL], Benign Symmetric Lipomatosis or Lanois-Bensaude Syndrome) is a metabolic condition characterized by the growth of fatty masses around the face, back of the head, neck, upper arms, abdomen, back and upper leg in a very specific pattern or distribution. Unlike the usual lipoma, these benign, fatty masses are not enclosed within a membranous capsule with very distinct boundaries. It is because of this characteristic, as well as the absolute symmetry in their occurrence, that the condition is often dismissed as simple obesity.
  • Dermatology Online Journal: Familial Multiple Lipomatosis Article by Brian R Toy, MD on this rare hereditary syndrome with the case history of an 89 year old man.
  • Lipomatosi di Launois-Bensaude (MSL) A site, in both Italian and English, providing a historical perspective of Madelung's Disease.
  • Madelung's Disease Describes the symptoms and diagnostic techniques for Madelung's disease, emphasizing the peculiarities of the disease compared to normal fatty deposits.
  • Madelung's Disease: Benign Symmetric Lipomatosis Provides an illustrated case study with notes on differential diagnoses.
  • NORD: Madelung's Disease The National Organization for Rare Disorders briefly describes this rare disorder (also known as Multiple Symmetrical Lipomatosis, Benign Symmetric Lipomatosis or Lanois-Bensaude Syndrome) and lists further reference information.
  • OMIM Entry 151800 Describes the form of Multiple Symmetric Lipomatosis (MSL) characterized by a collar of fat around the neck. The article suggests the cause to be a mitochondrial abnormality.
  • Soft Tissue Pathology Features images of the disease, taken with various scanning techniques.

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